DEPARTMENT OF INORGANIC CHEMISTRY
Main scientific directions of the Department:
- synthesis and investigation of the structure, properties and mechanism of biological action of complex compounds of transition metals containing metal-metal quartz bond. Bioorganic Chemistry of TransitionElements;
- development and research of anti-cancer and anti-hemolytic systems on the basis of cluster compounds of dyrenium (III);
- synthesis and research of carbonyl derivatives of rhenium (I) having fluorescent properties and can be used as supersensitive elements in electronics and as biological markers in medicine;
- Investigating mechanisms of cluster formation as a precondition for the formation of metallic crystalline lattice. The production of rhenium coatings and composite systems based on it, which exhibit a catalytic effect, including for the dopal exhaust gases of internal combustion engines of cars;
- development and research of new nitrate energy-intensive systems (together with the Department of Physical Chemistry).
Scientific work is carried out in accordance with the state budget issues of the Ministry of Education and Science of Ukraine : № 43/171290 “Purposeful synthesis of rhenium compounds in low oxidation stages and their nanoparticles with biological activity ” state registration number 0117U001159 (2017-2019) and No. 43/160499 “Compounds and dual-use materials based on coordination and hybrid systems » state registration number 0116U001717 (second half of the working day) (2016-2020).
Since 2017, the Department has being carried out the research work of Young Scientists № 43/171390 for №. 0117U006416 «Development of nanosystems for directed delivery of medicinal products » (the head – Associate Professor D.Ye. Kitova).
In 2010, the staff of the Department received 2 grants: the head of the Department Prof. O.V. Shtemenko received a grant from OSI’s Cambridge Colleges’ Hospitality Scheme for work at the University of Cambridge, and Ph.D. D.Ye. Kitovareceived a grant from Jackson State University (USA) to conduct studies to obtain nano-liposomes with encapsulated rhenium compounds to enhance the effectiveness of their biochemical effects. In addition, Prof. O.V. Shtemenko and D.Ye. Kitovaand D.V. Bobukhov performed research on the topic of their dissertation under the DAAD program (DeutscherAkademicherAustauschDienst) at the universities of Dortmund and Bochum ( Germany ).
Department of Inorganic Chemistry conducts close cooperation and coordination of work with the National Academy of Sciences of Ukraine (Scientific Council on the Problem “Inorganic Chemistry” of the National Academy of Sciences of Ukraine), the Institute of General and Inorganic Chemistry after Vernadsky National Academy of Sciences of Ukraine, Institute of Biochemistry after Palladin NAS of Ukraine, Institute of Geotechnical Mechanics of the National Academy of Sciences of Ukraine , Institute of Cell Biology of the National Academy of Sciences of Ukraine, Institute of Gastroenterology of the AMSU,Physico-Chemical Institute of the National Academy of Sciences of Ukraine and other leading Ukrainian universities.
According to the agreements on scientific and technical cooperation, joint scientific researches and consultations with the following foreign organizations are carried out:
- obtaining a nanolipos with encapsulated rhenium compounds from Jackson University, USA;
- research of interaction of complexes of metals with nucleotides and other biomolecules as models of the system “metal – DNA”. UniversityAutonomicdeMadrid, Spain;
- Study of the biological activity of complex rhenium compounds: Institude of Cardiovascular Sciences, Winnipeg, Canada;
- Research of biological activity of complex compounds of rhenium and technetium: SCPM, Bastia, France;
- study of the process of thermolysis of rhenium carbonyls: INSAMET Tecnalia, San Sebastian, Spain;
- synthesis and research of cluster compounds of rhenium (III) with nucleic bases: TU Dortmund, Germany;
- synthesis and research of coordination compounds of rhenium (I) with biopolymers: Ruhr University (Bochum), Germany.
Department of Inorganic Chemistry pays great attention to work with students. In 2010, 8 students took part in the scientific activity of the Department, two of whom personally participated in the 5th International Symposium on Bioorganometallic Chemistry, which was held at the Ruhr-Universitat (Bochum), Germany.
From 2011 to 2014,O.A. Golichenkoand I.L. Kovalenkowere in doctoral studies for profound work on a doctoral dissertation.
Awarding of the contest winners “Young Scientists – Dnipropetrovsk Region” (2017)